Exosome Facial vs PRP Facial — the short answer
An Exosome Facial uses lab-cultivated cell-signaling vesicles (with concentrated, standardized growth factors) applied topically after microchanneling — fast, no blood draw, $450, 75 minutes, minimal downtime. A PRP Facial uses growth factors drawn from your own blood, delivered via microneedling — autologous, animal-free, decades of clinical data, $250, requires a blood draw, 24-48 hours of redness. PRF is a slower-release upgrade of PRP with roughly ten times more growth factors and the body's own stem cells. Choose Exosome for speed and intensity, PRP for cost and "your-blood-only" purity, PRF for under-eyes and the most natural-biologic potency.
Want fastest results, no needles in your arm, vegan-friendly biologics? Exosome ($450). Want autologous, animal-free, lowest cost? PRP ($250). Want PRP's natural source but ~10x potency and great under-eye results? PRF. Many clients combine them — exosomes layered on PRP/PRF microneedling is Dr. Flávio's signature regenerative protocol.
Which one should you choose?
Use this decision matrix to narrow down before your consultation. There's no single "best" regenerative facial — only the one best matched to your goals, comfort level, and budget.
I want the fastest visible glow
Exosomes are highly concentrated and standardized. Many clients see a glow in 3-5 days; full brightening at 2-3 weeks.
Pick: ExosomeI'm needle-shy or hate blood draws
Exosomes don't require a blood draw. Only the microchanneling step uses fine needles.
Pick: ExosomeI want the lowest-cost regenerative facial
PRP is the most accessible regenerative option and still highly effective with a series.
Pick: PRPI want a fully autologous biologic (no lab-grown anything)
PRP and PRF use only what your body produces. Nothing synthetic, no animal sourcing.
Pick: PRP or PRFI have under-eye darkness or hollowing
PRF's slow-release fibrin gel is the standard of care in that delicate zone.
Pick: PRFI'm recovering from laser, microneedling, or peel
Exosomes dramatically accelerate healing — they're often added post-procedure.
Pick: ExosomeI want hair restoration
PRP/PRF are the gold standard for hair restoration injections.
Pick: PRP (scalp)I want the maximum-impact "everything" session
Combine microneedling with PRF and a topical exosome serum in one visit.
Pick: ComboSide-by-side comparison table
The honest, no-marketing-fluff breakdown of how all three regenerative facials stack up at Solace Wellness Aesthetics.
| Exosome Facial | PRP Facial | PRF Facial | |
|---|---|---|---|
| Source of growth factors | Lab-cultivated from human stem cells | Your own blood (autologous) | Your own blood (autologous) |
| Cost (per session) | $450 | $250 | $250 |
| Treatment duration | ~75 minutes | ~60 minutes (incl. draw + spin) | ~60 minutes (incl. draw + spin) |
| Downtime | Minimal — pink 12-24 hrs | 24-48 hrs redness | 24-48 hrs redness + mild swelling |
| Best for | Brightening, post-procedure healing, barrier repair, fast glow | Overall rejuvenation, fine lines, texture, scarring, hair | Under-eyes, deeper rejuvenation, fine lines, scars |
| Sessions for transformation | 1-3, spaced 4-6 weeks | 3-4, spaced 4-6 weeks | 2-3, spaced 4-6 weeks |
| Results timeline | Glow at 3-5 days · peak 2-4 weeks | Visible at 3-4 weeks · peak at 3 months | Visible at 1-2 weeks · peak at 3 months |
| Vegan / animal-free? | Yes — human stem-cell derived, not animal | Yes — your own blood | Yes — your own blood |
| Requires blood draw? | No | Yes (small) | Yes (small) |
| Growth factor concentration | Very high · lab-standardized | Baseline · varies per person | ~10x PRP · stem cells included |
| Maintenance | Every 6-12 months | Every 6-12 months | Every 6-12 months |
Option 1: Exosome Facial — $450
Exosome Facial
The Exosome Facial is the most advanced regenerative facial available at Solace. Exosomes are microscopic vesicles released by stem cells — essentially tiny packages of growth factors, peptides, mRNA, and signaling proteins. When delivered into the dermis after microchanneling, they instruct your skin cells to behave like younger, healthier cells: produce more collagen, repair the barrier, calm inflammation, and turn over pigment.
Because the exosome serum is lab-cultivated and standardized, every session delivers a consistent, concentrated dose — unlike PRP, which depends on your hydration, platelet count, and blood quality on the day. Dr. Flávio uses clinical-grade exosome products from reputable, lab-tested suppliers. The treatment is needle-free in the sense that there's no blood draw — only the microchannel step uses fine needles.
Best for: clients who want the fastest visible glow, are recovering from laser or peels, have stubborn redness or barrier damage, are needle-shy, or want a "high-performance" facial without the downtime of injectables. Pair it with a HydraFacial or chemical peel for compounded results.
- No blood draw — ideal for needle-averse clients
- Standardized dose every session — predictable results
- Strongest barrier repair of the three options
- Cuts post-laser and post-microneedling downtime in half
Option 2: PRP Facial — $250
PRP Facial
The PRP (Platelet-Rich Plasma) Facial — sometimes called the "vampire facial" — is the original regenerative aesthetic treatment and has been in clinical use for over two decades. A small vial of your blood is drawn, spun in a centrifuge to separate the platelet-rich plasma, and then delivered into the dermis via microneedling. Your platelets release growth factors that signal collagen production, capillary repair, and tissue regeneration.
PRP's signature advantage is that it's 100% you. There's no allergic reaction risk, no foreign material, no lab cultivation. It's the most natural regenerative option available — for clients who value autologous biologics, animal-free sourcing, and a long clinical track record. Results build gradually over 8-12 weeks as collagen remodels, with peak appearance at the 3-month mark.
Best for: overall rejuvenation, fine lines, texture improvement, mild acne scarring, mild hyperpigmentation, hair restoration (scalp injections), and clients who prefer "nothing but my own body" treatments. PRP is also the most budget-friendly entry into regenerative aesthetics and works beautifully as a series.
- Autologous — derived from your own blood
- Decades of peer-reviewed clinical data
- Most affordable regenerative facial at Solace
- Also available for scalp / hair restoration
Option 3: PRF Facial — $250
PRF Facial
PRF (Platelet-Rich Fibrin) is the next-generation evolution of PRP. The blood is spun at a slower speed without anticoagulant, which produces a fibrin gel rather than a liquid plasma. That fibrin matrix traps platelets, white blood cells, and your body's own stem cells, then releases growth factors slowly over 7-14 days instead of the short burst PRP provides.
The result: roughly 10x the growth factor concentration of PRP, plus stem cell activity, plus a sustained-release profile that's ideal for delicate areas like under the eyes. PRF is the regenerative facial of choice when you want maximum natural potency — particularly for under-eye darkness, hollowing, and stubborn fine lines. It's also gentler on the system because no anticoagulant is added.
Best for: under-eye darkness and hollowing, deeper rejuvenation than PRP alone provides, clients who already love PRP but want stronger results, acne scarring, and post-laser recovery. PRF is also Dr. Flávio's first choice for hair restoration in clients seeking a slow-release, stem-cell-rich option.
- ~10x more growth factors than PRP
- Releases slowly over 7-14 days — sustained effect
- Includes your body's stem cells
- Gold standard for under-eye treatment
Can you combine them?
Yes — and at Solace it's often the smartest move. Combination protocols stack the unique advantages of each biologic into a single appointment, dramatically amplifying results without dramatically increasing downtime.
Dr. Flávio's signature regenerative combo: A full-face microneedling session with PRP or PRF injected into the dermis, followed by topical exosome serum applied to the freshly created microchannels, finished with red-light LED activation. You get autologous growth factors plus concentrated lab-cultivated exosome signaling plus mechanical collagen induction — all in one ~90-minute visit.
Other popular combinations:
- Exosome + PRF under-eye: PRF placed under the eyes for darkness and hollowing, with full-face exosome facial layered on top.
- Exosome + Chemical Peel: A medium-depth peel followed by exosomes the same week to speed healing and amplify brightening.
- PRP + Microneedling RF: Radiofrequency microneedling for collagen tightening, with PRP delivered into the channels for accelerated repair.
- PRF + Filler: PRF placed in tear troughs and around the mouth, combined with a small amount of hyaluronic acid filler for structure.
Combo pricing is discussed at consultation — many combinations come in below the sum of individual treatments. A consultation with Dr. Flávio is the fastest way to design the right stack for your skin.
How Solace sources and handles each biologic
All three regenerative facials at Solace Wellness Aesthetics are performed by Dr. Flávio, DNP, AACC, a board-certified provider with advanced training in regenerative aesthetics. PRP and PRF are processed in-clinic in a single visit using FDA-cleared centrifuge systems. Exosome products are clinical-grade, lab-tested, and sourced from reputable U.S. suppliers — never animal-derived, never grey-market. Every session uses sterile, single-use kits.
Each protocol begins with a discovery consultation to map your skin goals, medical history, and contraindications. Pricing is transparent and includes the full protocol — no surprise add-ons. CareCredit financing is available for treatment series and combination protocols.
Frequently Asked Questions
Which is better, exosome facial or PRP facial?
Exosomes typically deliver faster, more dramatic brightening and barrier repair because they carry concentrated, lab-standardized growth factors. PRP uses your own blood-derived growth factors and is the better choice if you want a fully autologous, animal-free treatment with decades of clinical data. The "better" option depends on your goals: speed and intensity (Exosome) vs. natural and autologous (PRP).
Is an exosome facial worth the extra cost over PRP?
If you want fastest visible results, post-laser or post-microneedling recovery, or you prefer not to do a blood draw, the Exosome Facial at $450 is usually worth it. For maintenance and clients who prefer autologous biologics, PRP at $250 delivers excellent value.
How are exosomes different from PRP?
PRP is plasma drawn and spun from your own blood — it contains your platelets and growth factors. Exosomes are lab-cultivated extracellular vesicles released by stem cells; they carry concentrated growth factors, peptides, and mRNA signals at a much higher density than PRP. Exosomes are standardized; PRP varies based on your blood quality, hydration, and platelet count.
Can you do exosomes and PRP together?
Yes — at Solace, Dr. Flávio frequently combines microneedling with PRP or PRF and a topical exosome serum in the same visit. This stacks autologous growth factors with concentrated exosome signaling for compounded results. Combination protocols are common for clients with significant aging, scarring, or post-laser recovery.
What is the downtime for exosome vs PRP?
Exosome Facial: minimal downtime, mild pinkness for 12-24 hours. PRP Facial (with microneedling): 24-48 hours of redness and possible mild swelling. PRF Facial: similar to PRP but slightly more swelling because the fibrin matrix is denser. All three allow makeup the next day.
Are exosomes vegan or animal-free?
The exosomes used at Solace are lab-cultivated from human stem cells (typically umbilical cord mesenchymal stem cells), not animal-derived. PRP and PRF are autologous — they come from your own blood — so they are also animal-free.
Do exosomes require a blood draw?
No. Exosome facials do not require a blood draw, which makes them ideal for needle-averse clients or anyone who prefers a faster, simpler appointment. PRP and PRF both require a small blood draw at the start of treatment.
How many sessions do I need?
Exosome Facial: many clients see noticeable results after a single session; 2-3 sessions spaced 4-6 weeks apart is typical for transformation. PRP Facial: 3-4 sessions. PRF Facial: 2-3 sessions. Maintenance every 6-12 months is recommended for all three.
Which regenerative facial is best for under-eye darkness?
PRF is the gold standard for under-eye darkness and hollowing because the fibrin gel releases growth factors slowly over 7-14 days in a delicate area. Many clients combine PRF under the eyes with a full-face exosome facial for a complete rejuvenation.
Is exosome facial FDA approved?
Topical exosome serums used in aesthetics are regulated as cosmetic products and applied topically after microchanneling — not injected. PRP and PRF are autologous biologic procedures performed in-clinic. Solace only uses lab-tested, clinical-grade exosome products from reputable U.S. suppliers.