Exosome Facial at Solace Wellness Aesthetics in Fort Myers, FL is $450, takes 75 min, with Minimal downtime.
An exosome facial uses lab-cultivated exosomes — microscopic cell messengers that carry growth factors, peptides, and signaling proteins — to instruct skin cells to regenerate. The result: dramatically accelerated healing, brightening, firming, and barrier repair. Exosomes are the frontier of regenerative aesthetics, used by dermatologists for post-procedure recovery and ongoing skin optimization.
Investment
$450
Duration
75 min
Downtime
Minimal
Provider
Dr. Flávio
Wondering which regenerative facial is right for you? Read our Exosome Facial vs PRP Facial Buyer's Guide for a side-by-side comparison of cost, downtime, results, and sessions.
The Treatment
How Exosome Facial works
An exosome facial uses lab-cultivated exosomes — microscopic cell messengers that carry growth factors, peptides, and signaling proteins — to instruct skin cells to regenerate. The result: dramatically accelerated healing, brightening, firming, and barrier repair. Exosomes are the frontier of regenerative aesthetics, used by dermatologists for post-procedure recovery and ongoing skin optimization.
Deep Cleanse & Prep
Skin is cleansed, lightly exfoliated, and prepped to maximize absorption.
Microchanneling Phase
Light microneedling at 0.5mm creates microscopic channels — entry routes for exosomes to penetrate deeply.
Exosome Serum Application
Clinical-grade exosome serum (lyophilized, lab-controlled) is generously applied to entire face and neck.
LED Activation
Red and near-infrared LED therapy activates exosome signaling and amplifies cellular response.
Recovery Mask
Hyaluronic acid + soothing mask seals serums in. Skin barrier feels noticeably stronger by walkout.
What You'll Notice
Benefits of Exosome Facial
Accelerated post-procedure healing (cuts microneedling/peel/laser downtime in half)
Visibly brighter, more even skin tone within 7-14 days
Strengthened skin barrier — less reactivity, better tolerance to actives
Stimulates skin's own regenerative response (cumulative)
Reduces inflammation and redness
Improves texture and fine line appearance
Best For
Who should book Exosome Facial?
Post-procedure recovery (after microneedling, deep peels, laser), sensitive or reactive skin needing barrier repair, premature aging signs, those wanting cutting-edge cell-level regeneration without synthetic ingredients.
Recovery & Results
What to expect
Same day
Skin feels stronger, barrier improved
Day 3-7
Brightening visible. Inflammation reduces.
Week 2-4
Tone evens. Texture refines.
3 sessions
Maximum cumulative regenerative response
Before & After Your Exosome Facial
▣ Before Your Treatment
Arrive with clean, makeup-free skin
Avoid retinoids and exfoliating acids 3 days prior
Avoid prolonged sun exposure 2 weeks before
Stay hydrated — drink 8+ glasses of water daily the week before
No active rashes, sunburns, or open wounds on treatment area
▣ After Your Treatment
Apply SPF 30+ every morning — sun sensitivity is elevated 48 hours post-treatment
Avoid retinoids, vitamin C, and exfoliating acids for 48 hours
Keep skin hydrated with gentle, fragrance-free moisturizer
No intense heat (sauna, steam, hot yoga) for 24–48 hours
Results are visible immediately and continue improving over 7–14 days
Frequently Asked
Exosome Facial — common questions
Exosomes are nanoscale vesicles released by cells that contain growth factors, peptides, proteins, and signaling RNA. In aesthetics, they're isolated, purified, and applied topically (or via microchanneling) to deliver cellular instructions for skin regeneration — without using actual living cells.
$450 per session at Solace Wellness Aesthetics. Most patients see optimal results from a series of 3 sessions spaced 4-6 weeks apart. CareCredit financing available.
PRP/PRF uses YOUR blood-derived growth factors. Exosomes use lab-isolated cellular messengers — typically more potent, more consistent in concentration, and don't require a blood draw. Both are excellent; exosomes are newer and more concentrated.
Yes — exosomes used at Solace are FDA-cleared, lab-produced, and ethically sourced. No animal cells, no donor tissue. Used by dermatologists nationwide for post-procedure recovery.
Absolutely — exosomes work synergistically with microneedling. We often pair them: microneedling creates channels, exosomes deliver instructions through those channels. Best of both worlds.
Minimal — 4-6 hours of mild redness, similar to a light facial. Some patients return to work immediately.
Skin feels stronger same day. Brightening visible 7-10 days. Best results visible after a 3-session series.
Yes — in fact, sensitive skin often responds remarkably well because exosomes specifically calm inflammation and strengthen the skin barrier. Ideal for rosacea-prone and reactive skin types.
The Exo Booster Facial at Solace Wellness Aesthetics is $300. This pairs HydraFacial technology with exosome infusion for advanced skin regeneration and brightening. Individual exosome serum treatments applied post-procedure are available at various price points. Book a consultation to discuss which exosome protocol matches your skin goals.
Exosomes are nano-sized extracellular vesicles — cell-to-cell signaling messengers that carry proteins, lipids, and genetic material (mRNA, microRNA) that instruct recipient cells to activate repair, anti-inflammatory, and regenerative pathways. In aesthetics, exosomes derived from stem cells are applied to the skin (or injected) to stimulate fibroblast activity, reduce inflammation, accelerate cellular turnover, and promote collagen production. They operate at a fundamentally different (and deeper) level than standard growth factor serums.
PRP/PRF uses your own blood-derived growth factors — a natural but limited quantity. Exosome serums contain billions of signaling particles derived from laboratory-cultured stem cells, delivering a far higher concentration of regenerative signals. Exosomes also carry microRNA that can modulate gene expression in recipient cells, potentially affecting melanin production (brightening), inflammation response, and collagen synthesis at a genetic level. Exosomes are newer technology with excellent emerging evidence for skin rejuvenation.
Exosome facial treatment is highly effective for: post-laser and post-procedure recovery (accelerates healing by 30–50%), hyperpigmentation and melasma, chronic inflammation (rosacea-adjacent), skin dullness and uneven texture, early anti-aging, and hair restoration. The combination with HydraFacial in the Exo Booster treatment is ideal for clients wanting maximum brightness, plumpness, and a sustained glow result.
The Biology
What Exosomes Actually Do to Your Skin Cells
An exosome is a nano-sized vesicle — between 30 and 150 nanometers in diameter — released naturally by cells as part of intercellular communication. Every cell in your body produces and receives exosomes. They're the body's version of a text message: a precisely packaged signal carrying instructions from one cell to another.
In the context of skin rejuvenation, the exosomes used at Solace are derived from mesenchymal stem cells (MSCs) — a cell type that naturally produces regenerative signaling molecules in high concentrations. These MSC-derived exosomes are isolated, purified, and concentrated in the laboratory. What you receive during treatment is a standardized concentration of biological messengers carrying:
Proteins and peptides: Including collagen-stimulating peptides, anti-inflammatory cytokines, and barrier-strengthening proteins
MicroRNA: Regulatory RNA that modulates gene expression in your skin cells — influencing pigmentation pathways, inflammation control, and repair signaling at the genetic level
Lipids: Bioactive lipids that restore membrane integrity and contribute to barrier function repair
The critical distinction from serums: exosomes are not passive ingredients — they are active biological communicators that enter skin cells and alter cellular behavior. A serum delivers nutrients to the cell surface. An exosome delivers instructions that change what the cell does.
Why Topical Delivery + Microchanneling Matters
Exosomes are too large to penetrate intact skin on their own — their 30–150nm size means the stratum corneum's 100–200nm pore structure is the gating factor. Microchanneling (the shallow microneedling used in the Exosome Facial) creates temporary channels through the stratum corneum and epidermis, allowing exosome delivery directly to the dermis — where fibroblasts, the collagen-producing cells, reside. Without these channels, exosome serums applied topically achieve minimal dermal penetration. The combination is what makes the treatment clinically meaningful.
Clinical Results
What the Research Shows About Exosome Skin Therapy
The clinical evidence for MSC-derived exosomes in aesthetics is growing rapidly. Key findings from peer-reviewed research:
Collagen Stimulation
Multiple in vitro studies show MSC exosomes increase Type I and Type III collagen production in human fibroblasts by 2–5x baseline, with the effect mediated through the TGF-β1 pathway. Clinical studies in patients show measurable increases in skin firmness (Cutometer measurement) after a series of 3 exosome treatments.
Post-Procedure Recovery
The strongest clinical application for exosomes is post-procedure recovery. Dermatology studies show that exosome application after laser resurfacing or microneedling reduces recovery time by 30–50% and significantly decreases post-inflammatory erythema compared to standard post-care. This is why many dermatologists now use exosomes routinely after ablative procedures.
Hyperpigmentation
MicroRNA carried in MSC exosomes modulates the MITF pathway — the master regulator of melanocyte activity. Multiple clinical trials show measurable reduction in melanin index (skin darkness) and more even tone distribution after 4–6 weeks of exosome treatment.
Barrier Repair
Exosomes upregulate the expression of claudin, occludin, and filaggrin — structural proteins that form the skin barrier. Patients with chronically compromised barriers (eczema-prone, sensitive skin, post-isotretinoin) show measurable TEWL (transepidermal water loss) reduction after exosome treatment series.
Exosomes vs Other Regenerative Treatments
How Exosome Facial Compares to PRP, PRF, and Standard Facials
vs PRP Facial: PRP uses your blood-derived platelets. Concentration varies by individual (low platelets = weaker PRP). PRP contains pro-inflammatory cytokines that can be problematic for sensitive/rosacea skin. Exosomes are standardized, contain no pro-inflammatory components, and include microRNA that PRP lacks. For sensitive skin and inflammatory conditions: exosomes preferred. For hair restoration and autologous preference: PRP/PRF preferred.
vs Regular Facial: A regular facial works at the surface — cleansing, exfoliation, topical hydration. Results last 1–2 weeks and are entirely surface-level. An exosome facial triggers actual cellular changes at the dermis level — collagen production, barrier repair, pigmentation modulation. Results compound over sessions and include structural improvements lasting months.
vs Microneedling Alone: Standard microneedling triggers collagen production through mechanical injury + standard growth factor serums. Exosome-enhanced microneedling adds the cellular signaling payload — studies show exosome microneedling produces faster and more visible collagen response than microneedling with standard serums.
vs Chemical Peel: Chemical peels address surface pigmentation and texture through acid exfoliation. Exosome facials address cellular biology — regeneration, inflammation, and collagen production. Complementary treatments; exosome facial is superior for repair, sensitivity, and barrier concerns.
Fort Myers, Cape Coral & Estero
Exosome Facial Near Me — Fort Myers Area
Solace Wellness Aesthetics is Southwest Florida's only medical aesthetics practice currently offering standardized MSC-derived exosome facial treatments with microchanneling delivery. Located at 12545 New Brittany Blvd, Building 26, Fort Myers, FL 33907, we serve patients from Fort Myers, Cape Coral, Estero, Bonita Springs, and Naples. Exosome Facial appointments require a free consultation for first-time patients — call (239) 323-9549 or book online. Pricing: $450/session. Package of 3 available.
Conveniently located at 12545 New Brittany Blvd, Fort Myers, FL, Solace Wellness Aesthetics serves clients from Fort Myers, Cape Coral, Estero, Bonita Springs, Naples, and throughout Southwest Florida. If you're searching for a medical spa near you in SWFL, we're minutes away.
Ready to book?
Schedule your Exosome Facial appointment online — same-day availability often available.